C49
Non-Billable

Malignant neoplasm of other connective and soft tissue

Non-Billable / Non-Specific Code

What is Malignant neoplasm of other connective and soft tissue?

ICD-10-CM C49 is the diagnosis code for Malignant neoplasm of other connective and soft tissue. This code falls under the section "Malignant neoplasms of mesothelial and soft tissue" within Chapter 2 — Neoplasms (C00-D49). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

⛔ Excludes1
â„šī¸ Excludes2

Coding Guidelines for C49

⛔ Type 1 Excludes (Never code together)

The following conditions should never be coded at the same time as C49. They are mutually exclusive:

  • malignant neoplasm of cartilage (of):
  • articular (C40-C41)
  • larynx (C32.3)
  • nose (C30.0)
  • malignant neoplasm of connective tissue of breast (C50.-)

â„šī¸ Type 2 Excludes (Code separately if applicable)

The following conditions are not included in C49. If the patient has both, code each condition separately:

  • Kaposi's sarcoma of soft tissue (C46.1)
  • malignant neoplasm of heart (C38.0)
  • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
  • malignant neoplasm of peritoneum (C48.2)
  • malignant neoplasm of retroperitoneum (C48.0)
  • malignant neoplasm of uterine ligament (C57.3)
  • mesothelioma (C45.-)

ICD-10-CM Code Hierarchy

Understanding where C49 sits in the ICD-10-CM classification helps ensure proper coding:

Current CodeC49 — Malignant neoplasm of other connective and soft tissue
Sub-Codes 10 entries
C49.0Malignant neoplasm of connective and soft tissue of head, face and neckBillableC49.1Malignant neoplasm of connective and soft tissue of upper limb, including shoulderNon-BillableC49.10Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulderBillableC49.11Malignant neoplasm of connective and soft tissue of right upper limb, including shoulderBillableC49.12Malignant neoplasm of connective and soft tissue of left upper limb, including shoulderBillableC49.2Malignant neoplasm of connective and soft tissue of lower limb, including hipNon-BillableC49.20Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hipBillableC49.21Malignant neoplasm of connective and soft tissue of right lower limb, including hipBillableC49.22Malignant neoplasm of connective and soft tissue of left lower limb, including hipBillableC49.3Malignant neoplasm of connective and soft tissue of thoraxBillableC49.4Malignant neoplasm of connective and soft tissue of abdomenBillableC49.5Malignant neoplasm of connective and soft tissue of pelvisBillableC49.6Malignant neoplasm of connective and soft tissue of trunk, unspecifiedBillableC49.8Malignant neoplasm of overlapping sites of connective and soft tissueBillableC49.9Malignant neoplasm of connective and soft tissue, unspecifiedBillableC49.AGastrointestinal stromal tumorNon-BillableC49.A0Gastrointestinal stromal tumor, unspecified siteBillableC49.A1Gastrointestinal stromal tumor of esophagusBillableC49.A2Gastrointestinal stromal tumor of stomachBillableC49.A3Gastrointestinal stromal tumor of small intestineBillableC49.A4Gastrointestinal stromal tumor of large intestineBillableC49.A5Gastrointestinal stromal tumor of rectumBillableC49.A9Gastrointestinal stromal tumor of other sitesBillable
Related Codes

Frequently Asked Questions

Is C49 a billable ICD-10-CM code?

No, C49 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does C49 mean?

C49 is the ICD-10-CM diagnosis code for "Malignant neoplasm of other connective and soft tissue". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What section is C49 in?

C49 is located in Section C45-C49 — "Malignant neoplasms of mesothelial and soft tissue" within Chapter 2 of the ICD-10-CM Tabular List.

What are the sub-codes of C49?

C49 has 10 sub-code(s) that provide more specific detail: C49.0, C49.1, C49.2, C49.3, C49.4 and more.

When should I use C49?

Use C49 when the patients documented diagnosis matches "Malignant neoplasm of other connective and soft tissue" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Malignant neoplasm of other connective and soft tissue?

The ICD-10-CM code for Malignant neoplasm of other connective and soft tissue is C49.

Can C49 be used for primary diagnosis?

No, C49 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is C49 in?

C49 is in Chapter 2 of the ICD-10-CM Tabular List.

What conditions are excluded from C49?

Type 1 Excludes for C49 include: malignant neoplasm of cartilage (of):; articular (C40-C41); larynx (C32.3) and more.

Is C49 valid for 2026?

Yes, C49 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousC48.8Malignant neoplasm of overlapping sites of retroperitoneum and peritoneumNext →C49.0Malignant neoplasm of connective and soft tissue of head, face and neck
Code Details
C49
Malignant neoplasm of other connective and soft tissue
Non-Billable / Non-Specific Code
2 — Neoplasms (C00-D49)
C45-C49 — Malignant neoplasms of mesothelial and soft tissue
2026 ICD-10-CM