Billable / Specific Code
ICD-10-CM D57.459 is the diagnosis code for Sickle-cell thalassemia beta plus with crisis, unspecified. This code falls under the section "Hemolytic anemias" within Chapter 3 — Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89). It is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.
Understanding where D57.459 sits in the ICD-10-CM classification helps ensure proper coding:
Yes, D57.459 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
D57.459 is the ICD-10-CM diagnosis code for "Sickle-cell thalassemia beta plus with crisis, unspecified". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.
The parent code of D57.459 is D57.45 ("Sickle-cell thalassemia beta plus with crisis"). D57.459 provides a more specific classification within this category.
D57.459 is located in Section D55-D59 — "Hemolytic anemias" within Chapter 3 of the ICD-10-CM Tabular List.
Use D57.459 when the patients documented diagnosis matches "Sickle-cell thalassemia beta plus with crisis, unspecified" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.
The ICD-10-CM code for Sickle-cell thalassemia beta plus with crisis, unspecified is D57.459.
Yes, D57.459 can be used as a primary diagnosis code since it is billable and specific.
D57.459 is in Chapter 3 of the ICD-10-CM Tabular List.
Yes, D57.459 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.