D61.81
Non-Billable

Pancytopenia

Non-Billable / Non-Specific Code

What is Pancytopenia?

ICD-10-CM D61.81 is the diagnosis code for Pancytopenia. This code falls under the section "Aplastic and other anemias and other bone marrow failure syndromes" within Chapter 3 — Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

⛔ Excludes1
â„šī¸ Excludes2

Coding Guidelines for D61.81

⛔ Type 1 Excludes (Never code together)

The following conditions should never be coded at the same time as D61.81. They are mutually exclusive:

  • pancytopenia (due to) (with) aplastic anemia (D61.9)
  • pancytopenia (due to) (with) bone marrow infiltration (D61.82)
  • pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01)
  • pancytopenia (due to) (with) hairy cell leukemia (C91.4-)
  • pancytopenia (due to) (with) human immunodeficiency virus disease (B20.-)
  • pancytopenia (due to) (with) leukoerythroblastic anemia (D61.82)
  • pancytopenia (due to) (with) myeloproliferative disease (D47.1)

â„šī¸ Type 2 Excludes (Code separately if applicable)

The following conditions are not included in D61.81. If the patient has both, code each condition separately:

  • pancytopenia (due to) (with) myelodysplastic syndromes (D46.-)

ICD-10-CM Code Hierarchy

Understanding where D61.81 sits in the ICD-10-CM classification helps ensure proper coding:

Sub-Codes 3 entries
D61.810Antineoplastic chemotherapy induced pancytopeniaBillableD61.811Other drug-induced pancytopeniaBillableD61.818Other pancytopeniaBillable
Related Codes

Frequently Asked Questions

Is D61.81 a billable ICD-10-CM code?

No, D61.81 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does D61.81 mean?

D61.81 is the ICD-10-CM diagnosis code for "Pancytopenia". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What is the parent code of D61.81?

The parent code of D61.81 is D61.8 ("Other specified aplastic anemias and other bone marrow failure syndromes"). D61.81 provides a more specific classification within this category.

What section is D61.81 in?

D61.81 is located in Section D60-D64 — "Aplastic and other anemias and other bone marrow failure syndromes" within Chapter 3 of the ICD-10-CM Tabular List.

What are the sub-codes of D61.81?

D61.81 has 3 sub-code(s) that provide more specific detail: D61.810, D61.811, D61.818.

When should I use D61.81?

Use D61.81 when the patients documented diagnosis matches "Pancytopenia" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Pancytopenia?

The ICD-10-CM code for Pancytopenia is D61.81.

Can D61.81 be used for primary diagnosis?

No, D61.81 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is D61.81 in?

D61.81 is in Chapter 3 of the ICD-10-CM Tabular List.

What conditions are excluded from D61.81?

Type 1 Excludes for D61.81 include: pancytopenia (due to) (with) aplastic anemia (D61.9); pancytopenia (due to) (with) bone marrow infiltration (D61.82); pancytopenia (due to) (with) congenital (pure) red cell aplasia (D61.01) and more.

Is D61.81 valid for 2026?

Yes, D61.81 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousD61.8Other specified aplastic anemias and other bone marrow failure syndromesNext →D61.810Antineoplastic chemotherapy induced pancytopenia
Code Details
D61.81
Pancytopenia
Non-Billable / Non-Specific Code
3 — Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D60-D64 — Aplastic and other anemias and other bone marrow failure syndromes
2026 ICD-10-CM