Non-Billable / Non-Specific Code
ICD-10-CM E22 is the diagnosis code for Hyperfunction of pituitary gland. This code falls under the section "Disorders of other endocrine glands" within Chapter 4 — Endocrine, nutritional and metabolic diseases (E00-E89). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.
The following conditions should never be coded at the same time as E22. They are mutually exclusive:
Understanding where E22 sits in the ICD-10-CM classification helps ensure proper coding:
No, E22 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.
E22 is the ICD-10-CM diagnosis code for "Hyperfunction of pituitary gland". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.
E22 is located in Section E20-E35 — "Disorders of other endocrine glands" within Chapter 4 of the ICD-10-CM Tabular List.
E22 has 5 sub-code(s) that provide more specific detail: E22.0, E22.1, E22.2, E22.8, E22.9.
Use E22 when the patients documented diagnosis matches "Hyperfunction of pituitary gland" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.
The ICD-10-CM code for Hyperfunction of pituitary gland is E22.
No, E22 is non-billable. Use a more specific sub-code for primary diagnosis billing.
E22 is in Chapter 4 of the ICD-10-CM Tabular List.
Type 1 Excludes for E22 include: Cushing's syndrome (E24.-); Nelson's syndrome (E24.1); overproduction of ACTH not associated with Cushing's disease (E27.0) and more.
Yes, E22 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.