E34.321
Billable

Primary insulin-like growth factor-1 (IGF-1) deficiency

Billable / Specific Code

What is Primary insulin-like growth factor-1 (IGF-1) deficiency?

ICD-10-CM E34.321 is the diagnosis code for Primary insulin-like growth factor-1 (IGF-1) deficiency. This code falls under the section "Disorders of other endocrine glands" within Chapter 4 — Endocrine, nutritional and metabolic diseases (E00-E89). It is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

💡 Inclusions

Coding Guidelines for E34.321

✅ This Code Includes

  • Acid-labile subunit gene (IGFALS) defect
  • Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies
  • Growth hormone insensitivity syndrome (GHIS)
  • Insulin-like growth factor 1 gene (IGF1) defect
  • Laron type short stature
  • Severe primary insulin-like growth factor-1 deficiency (SPIGFD)
  • Signal transducer and activator of transcription 5B gene (STAT5b) defect

ICD-10-CM Code Hierarchy

Understanding where E34.321 sits in the ICD-10-CM classification helps ensure proper coding:

Current CodeE34.321 — Primary insulin-like growth factor-1 (IGF-1) deficiency
Related Codes

Frequently Asked Questions

Is E34.321 a billable ICD-10-CM code?

Yes, E34.321 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

What does E34.321 mean?

E34.321 is the ICD-10-CM diagnosis code for "Primary insulin-like growth factor-1 (IGF-1) deficiency". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What is the parent code of E34.321?

The parent code of E34.321 is E34.32 ("Genetic causes of short stature"). E34.321 provides a more specific classification within this category.

What section is E34.321 in?

E34.321 is located in Section E20-E35 — "Disorders of other endocrine glands" within Chapter 4 of the ICD-10-CM Tabular List.

When should I use E34.321?

Use E34.321 when the patients documented diagnosis matches "Primary insulin-like growth factor-1 (IGF-1) deficiency" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Primary insulin-like growth factor-1 (IGF-1) deficiency?

The ICD-10-CM code for Primary insulin-like growth factor-1 (IGF-1) deficiency is E34.321.

Can E34.321 be used for primary diagnosis?

Yes, E34.321 can be used as a primary diagnosis code since it is billable and specific.

What chapter is E34.321 in?

E34.321 is in Chapter 4 of the ICD-10-CM Tabular List.

Is E34.321 valid for 2026?

Yes, E34.321 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousE34.32Genetic causes of short statureNext →E34.322Insulin-like growth factor-1 (IGF-1) resistance
Code Details
E34.321
Primary insulin-like growth factor-1 (IGF-1) deficiency
Billable / Specific Code
4 — Endocrine, nutritional and metabolic diseases (E00-E89)
E20-E35 — Disorders of other endocrine glands
2026 ICD-10-CM