E72
Non-Billable

Other disorders of amino-acid metabolism

Non-Billable / Non-Specific Code

What is Other disorders of amino-acid metabolism?

ICD-10-CM E72 is the diagnosis code for Other disorders of amino-acid metabolism. This code falls under the section "Metabolic disorders" within Chapter 4 — Endocrine, nutritional and metabolic diseases (E00-E89). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

⛔ Excludes1

Coding Guidelines for E72

⛔ Type 1 Excludes (Never code together)

The following conditions should never be coded at the same time as E72. They are mutually exclusive:

  • disorders of:
  • aromatic amino-acid metabolism (E70.-)
  • branched-chain amino-acid metabolism (E71.0-E71.2)
  • fatty-acid metabolism (E71.3)
  • purine and pyrimidine metabolism (E79.-)
  • gout (M1A.-, M10.-)

ICD-10-CM Code Hierarchy

Understanding where E72 sits in the ICD-10-CM classification helps ensure proper coding:

Current CodeE72 — Other disorders of amino-acid metabolism
Sub-Codes 8 entries
E72.0Disorders of amino-acid transportNon-BillableE72.00Disorders of amino-acid transport, unspecifiedBillableE72.01CystinuriaBillableE72.02Hartnup's diseaseBillableE72.03Lowe's syndromeBillableE72.04CystinosisBillableE72.09Other disorders of amino-acid transportBillableE72.1Disorders of sulfur-bearing amino-acid metabolismNon-BillableE72.10Disorders of sulfur-bearing amino-acid metabolism, unspecifiedBillableE72.11HomocystinuriaBillableE72.12Methylenetetrahydrofolate reductase deficiencyBillableE72.19Other disorders of sulfur-bearing amino-acid metabolismBillableE72.2Disorders of urea cycle metabolismNon-BillableE72.20Disorder of urea cycle metabolism, unspecifiedBillableE72.21ArgininemiaBillableE72.22Arginosuccinic aciduriaBillableE72.23CitrullinemiaBillableE72.29Other disorders of urea cycle metabolismBillableE72.3Disorders of lysine and hydroxylysine metabolismBillableE72.4Disorders of ornithine metabolismBillableE72.5Disorders of glycine metabolismNon-BillableE72.50Disorder of glycine metabolism, unspecifiedBillableE72.51Non-ketotic hyperglycinemiaBillableE72.52TrimethylaminuriaBillableE72.53Primary hyperoxaluriaNon-BillableE72.530Primary hyperoxaluria, type 1BillableE72.538Other specified primary hyperoxaluriaBillableE72.539Primary hyperoxaluria, unspecifiedBillableE72.54Secondary hyperoxaluriaNon-BillableE72.540Dietary hyperoxaluriaBillableE72.541Enteric hyperoxaluriaBillableE72.548Other secondary hyperoxaluriaBillableE72.549Secondary hyperoxaluria, unspecifiedBillableE72.59Other disorders of glycine metabolismBillableE72.8Other specified disorders of amino-acid metabolismNon-BillableE72.81Disorders of gamma aminobutyric acid metabolismBillableE72.89Other specified disorders of amino-acid metabolismBillableE72.9Disorder of amino-acid metabolism, unspecifiedBillable
Related Codes

Frequently Asked Questions

Is E72 a billable ICD-10-CM code?

No, E72 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does E72 mean?

E72 is the ICD-10-CM diagnosis code for "Other disorders of amino-acid metabolism". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What section is E72 in?

E72 is located in Section E70-E88 — "Metabolic disorders" within Chapter 4 of the ICD-10-CM Tabular List.

What are the sub-codes of E72?

E72 has 8 sub-code(s) that provide more specific detail: E72.0, E72.1, E72.2, E72.3, E72.4 and more.

When should I use E72?

Use E72 when the patients documented diagnosis matches "Other disorders of amino-acid metabolism" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Other disorders of amino-acid metabolism?

The ICD-10-CM code for Other disorders of amino-acid metabolism is E72.

Can E72 be used for primary diagnosis?

No, E72 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is E72 in?

E72 is in Chapter 4 of the ICD-10-CM Tabular List.

What conditions are excluded from E72?

Type 1 Excludes for E72 include: disorders of:; aromatic amino-acid metabolism (E70.-); branched-chain amino-acid metabolism (E71.0-E71.2) and more.

Is E72 valid for 2026?

Yes, E72 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousE71.548Other peroxisomal disordersNext →E72.0Disorders of amino-acid transport
Code Details
E72
Other disorders of amino-acid metabolism
Non-Billable / Non-Specific Code
4 — Endocrine, nutritional and metabolic diseases (E00-E89)
E70-E88 — Metabolic disorders
2026 ICD-10-CM