Non-Billable / Non-Specific Code
ICD-10-CM T43.21 is the diagnosis code for Poisoning by, adverse effect of and underdosing of selective serotonin and norepinephrine reuptake inhibitors. This code falls under the section "Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances" within Chapter 19 — Injury, poisoning and certain other consequences of external causes (S00-T88). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.
Understanding where T43.21 sits in the ICD-10-CM classification helps ensure proper coding:
No, T43.21 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.
T43.21 is the ICD-10-CM diagnosis code for "Poisoning by, adverse effect of and underdosing of selective serotonin and norepinephrine reuptake inhibitors". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.
The parent code of T43.21 is T43.2 ("Poisoning by, adverse effect of and underdosing of other and unspecified antidepressants"). T43.21 provides a more specific classification within this category.
T43.21 is located in Section T36-T50 — "Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances" within Chapter 19 of the ICD-10-CM Tabular List.
T43.21 has 6 sub-code(s) that provide more specific detail: T43.211, T43.212, T43.213, T43.214, T43.215 and more.
Use T43.21 when the patients documented diagnosis matches "Poisoning by, adverse effect of and underdosing of selective serotonin and norepinephrine reuptake inhibitors" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.
The ICD-10-CM code for Poisoning by, adverse effect of and underdosing of selective serotonin and norepinephrine reuptake inhibitors is T43.21.
No, T43.21 is non-billable. Use a more specific sub-code for primary diagnosis billing.
T43.21 is in Chapter 19 of the ICD-10-CM Tabular List.
Yes, T43.21 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.