Non-Billable / Non-Specific Code
ICD-10-CM Z79.81 is the diagnosis code for Long term (current) use of agents affecting estrogen receptors and estrogen levels. This code falls under the section "Persons with potential health hazards related to family and personal history and certain conditions influencing health status" within Chapter 21 — Factors influencing health status and contact with health services (Z00-Z99). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.
The following conditions should never be coded at the same time as Z79.81. They are mutually exclusive:
Understanding where Z79.81 sits in the ICD-10-CM classification helps ensure proper coding:
No, Z79.81 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.
Z79.81 is the ICD-10-CM diagnosis code for "Long term (current) use of agents affecting estrogen receptors and estrogen levels". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.
The parent code of Z79.81 is Z79.8 ("Other long term (current) drug therapy"). Z79.81 provides a more specific classification within this category.
Z79.81 is located in Section Z77-Z99 — "Persons with potential health hazards related to family and personal history and certain conditions influencing health status" within Chapter 21 of the ICD-10-CM Tabular List.
Z79.81 has 3 sub-code(s) that provide more specific detail: Z79.810, Z79.811, Z79.818.
Use Z79.81 when the patients documented diagnosis matches "Long term (current) use of agents affecting estrogen receptors and estrogen levels" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.
The ICD-10-CM code for Long term (current) use of agents affecting estrogen receptors and estrogen levels is Z79.81.
No, Z79.81 is non-billable. Use a more specific sub-code for primary diagnosis billing.
Z79.81 is in Chapter 21 of the ICD-10-CM Tabular List.
Type 1 Excludes for Z79.81 include: hormone replacement therapy (Z79.890).
Yes, Z79.81 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.