Non-Billable / Non-Specific Code
ICD-10-CM D57.4 is the diagnosis code for Sickle-cell thalassemia. This code falls under the section "Hemolytic anemias" within Chapter 3 — Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.
Understanding where D57.4 sits in the ICD-10-CM classification helps ensure proper coding:
No, D57.4 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.
D57.4 is the ICD-10-CM diagnosis code for "Sickle-cell thalassemia". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.
The parent code of D57.4 is D57 ("Sickle-cell disorders"). D57.4 provides a more specific classification within this category.
D57.4 is located in Section D55-D59 — "Hemolytic anemias" within Chapter 3 of the ICD-10-CM Tabular List.
D57.4 has 6 sub-code(s) that provide more specific detail: D57.40, D57.41, D57.42, D57.43, D57.44 and more.
Use D57.4 when the patients documented diagnosis matches "Sickle-cell thalassemia" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.
The ICD-10-CM code for Sickle-cell thalassemia is D57.4.
No, D57.4 is non-billable. Use a more specific sub-code for primary diagnosis billing.
D57.4 is in Chapter 3 of the ICD-10-CM Tabular List.
Yes, D57.4 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.