D68.5
Non-Billable

Primary thrombophilia

Non-Billable / Non-Specific Code

What is Primary thrombophilia?

ICD-10-CM D68.5 is the diagnosis code for Primary thrombophilia. This code falls under the section "Coagulation defects, purpura and other hemorrhagic conditions" within Chapter 3 — Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

💡 Inclusions
⛔ Excludes1

Coding Guidelines for D68.5

✅ This Code Includes

  • Primary hypercoagulable states

⛔ Type 1 Excludes (Never code together)

The following conditions should never be coded at the same time as D68.5. They are mutually exclusive:

  • antiphospholipid syndrome (D68.61)
  • lupus anticoagulant (D68.62)
  • secondary activated protein C resistance (D68.69)
  • secondary antiphospholipid antibody syndrome (D68.69)
  • secondary lupus anticoagulant with hypercoagulable state (D68.69)
  • secondary systemic lupus erythematosus [SLE] inhibitor with hypercoagulable state (D68.69)
  • systemic lupus erythematosus [SLE] inhibitor finding without diagnosis (R76.0)
  • systemic lupus erythematosus [SLE] inhibitor with hemorrhagic disorder (D68.312)
  • thrombotic thrombocytopenic purpura (M31.19)

ICD-10-CM Code Hierarchy

Understanding where D68.5 sits in the ICD-10-CM classification helps ensure proper coding:

Sub-Codes 3 entries
D68.51Activated protein C resistanceBillableD68.52Prothrombin gene mutationBillableD68.59Other primary thrombophiliaBillable
Related Codes

Frequently Asked Questions

Is D68.5 a billable ICD-10-CM code?

No, D68.5 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does D68.5 mean?

D68.5 is the ICD-10-CM diagnosis code for "Primary thrombophilia". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What is the parent code of D68.5?

The parent code of D68.5 is D68 ("Other coagulation defects"). D68.5 provides a more specific classification within this category.

What section is D68.5 in?

D68.5 is located in Section D65-D69 — "Coagulation defects, purpura and other hemorrhagic conditions" within Chapter 3 of the ICD-10-CM Tabular List.

What are the sub-codes of D68.5?

D68.5 has 3 sub-code(s) that provide more specific detail: D68.51, D68.52, D68.59.

When should I use D68.5?

Use D68.5 when the patients documented diagnosis matches "Primary thrombophilia" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Primary thrombophilia?

The ICD-10-CM code for Primary thrombophilia is D68.5.

Can D68.5 be used for primary diagnosis?

No, D68.5 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is D68.5 in?

D68.5 is in Chapter 3 of the ICD-10-CM Tabular List.

What conditions are excluded from D68.5?

Type 1 Excludes for D68.5 include: antiphospholipid syndrome (D68.61); lupus anticoagulant (D68.62); secondary activated protein C resistance (D68.69) and more.

Is D68.5 valid for 2026?

Yes, D68.5 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousD68.4Acquired coagulation factor deficiencyNext →D68.51Activated protein C resistance
Code Details
D68.5
Primary thrombophilia
Non-Billable / Non-Specific Code
3 — Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D65-D69 — Coagulation defects, purpura and other hemorrhagic conditions
2026 ICD-10-CM