E21
Non-Billable

Hyperparathyroidism and other disorders of parathyroid gland

Non-Billable / Non-Specific Code

What is Hyperparathyroidism and other disorders of parathyroid gland?

ICD-10-CM E21 is the diagnosis code for Hyperparathyroidism and other disorders of parathyroid gland. This code falls under the section "Disorders of other endocrine glands" within Chapter 4 — Endocrine, nutritional and metabolic diseases (E00-E89). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

⛔ Excludes1
â„šī¸ Excludes2

Coding Guidelines for E21

⛔ Type 1 Excludes (Never code together)

The following conditions should never be coded at the same time as E21. They are mutually exclusive:

  • adult osteomalacia (M83.-)
  • ectopic hyperparathyroidism (E34.2)
  • hungry bone syndrome (E83.81)
  • infantile and juvenile osteomalacia (E55.0)

â„šī¸ Type 2 Excludes (Code separately if applicable)

The following conditions are not included in E21. If the patient has both, code each condition separately:

  • familial hypocalciuric hypercalcemia (E83.52)

ICD-10-CM Code Hierarchy

Understanding where E21 sits in the ICD-10-CM classification helps ensure proper coding:

Current CodeE21 — Hyperparathyroidism and other disorders of parathyroid gland
Sub-Codes 6 entries
E21.0Primary hyperparathyroidismBillableE21.1Secondary hyperparathyroidism, not elsewhere classifiedBillableE21.2Other hyperparathyroidismBillableE21.3Hyperparathyroidism, unspecifiedBillableE21.4Other specified disorders of parathyroid glandBillableE21.5Disorder of parathyroid gland, unspecifiedBillable
Related Codes

Frequently Asked Questions

Is E21 a billable ICD-10-CM code?

No, E21 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does E21 mean?

E21 is the ICD-10-CM diagnosis code for "Hyperparathyroidism and other disorders of parathyroid gland". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What section is E21 in?

E21 is located in Section E20-E35 — "Disorders of other endocrine glands" within Chapter 4 of the ICD-10-CM Tabular List.

What are the sub-codes of E21?

E21 has 6 sub-code(s) that provide more specific detail: E21.0, E21.1, E21.2, E21.3, E21.4 and more.

When should I use E21?

Use E21 when the patients documented diagnosis matches "Hyperparathyroidism and other disorders of parathyroid gland" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Hyperparathyroidism and other disorders of parathyroid gland?

The ICD-10-CM code for Hyperparathyroidism and other disorders of parathyroid gland is E21.

Can E21 be used for primary diagnosis?

No, E21 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is E21 in?

E21 is in Chapter 4 of the ICD-10-CM Tabular List.

What conditions are excluded from E21?

Type 1 Excludes for E21 include: adult osteomalacia (M83.-); ectopic hyperparathyroidism (E34.2); hungry bone syndrome (E83.81) and more.

Is E21 valid for 2026?

Yes, E21 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousE20.9Hypoparathyroidism, unspecifiedNext →E21.0Primary hyperparathyroidism
Code Details
E21
Hyperparathyroidism and other disorders of parathyroid gland
Non-Billable / Non-Specific Code
4 — Endocrine, nutritional and metabolic diseases (E00-E89)
E20-E35 — Disorders of other endocrine glands
2026 ICD-10-CM