I21
Non-Billable

Acute myocardial infarction

Non-Billable / Non-Specific Code

What is Acute myocardial infarction?

ICD-10-CM I21 is the diagnosis code for Acute myocardial infarction. This code falls under the section "Ischemic heart diseases" within Chapter 9 — Diseases of the circulatory system (I00-I99). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

â„šī¸ Excludes2

Coding Guidelines for I21

â„šī¸ Type 2 Excludes (Code separately if applicable)

The following conditions are not included in I21. If the patient has both, code each condition separately:

  • old myocardial infarction (I25.2)
  • postmyocardial infarction syndrome (I24.1)
  • subsequent type 1 myocardial infarction (I22.-)

ICD-10-CM Code Hierarchy

Understanding where I21 sits in the ICD-10-CM classification helps ensure proper coding:

Sub-Codes 8 entries
I21.0ST elevation (STEMI) myocardial infarction of anterior wallNon-BillableI21.01ST elevation (STEMI) myocardial infarction involving left main coronary arteryBillableI21.02ST elevation (STEMI) myocardial infarction involving left anterior descending coronary arteryBillableI21.09ST elevation (STEMI) myocardial infarction involving other coronary artery of anterior wallBillableI21.1ST elevation (STEMI) myocardial infarction of inferior wallNon-BillableI21.11ST elevation (STEMI) myocardial infarction involving right coronary arteryBillableI21.19ST elevation (STEMI) myocardial infarction involving other coronary artery of inferior wallBillableI21.2ST elevation (STEMI) myocardial infarction of other sitesNon-BillableI21.21ST elevation (STEMI) myocardial infarction involving left circumflex coronary arteryBillableI21.29ST elevation (STEMI) myocardial infarction involving other sitesBillableI21.3ST elevation (STEMI) myocardial infarction of unspecified siteBillableI21.4Non-ST elevation (NSTEMI) myocardial infarctionBillableI21.9Acute myocardial infarction, unspecifiedBillableI21.AOther type of myocardial infarctionNon-BillableI21.A1Myocardial infarction type 2BillableI21.A9Other myocardial infarction typeBillableI21.BMyocardial infarction with coronary microvascular dysfunctionBillable
Related Codes

Frequently Asked Questions

Is I21 a billable ICD-10-CM code?

No, I21 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does I21 mean?

I21 is the ICD-10-CM diagnosis code for "Acute myocardial infarction". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What section is I21 in?

I21 is located in Section I20-I25 — "Ischemic heart diseases" within Chapter 9 of the ICD-10-CM Tabular List.

What are the sub-codes of I21?

I21 has 8 sub-code(s) that provide more specific detail: I21.0, I21.1, I21.2, I21.3, I21.4 and more.

When should I use I21?

Use I21 when the patients documented diagnosis matches "Acute myocardial infarction" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Acute myocardial infarction?

The ICD-10-CM code for Acute myocardial infarction is I21.

Can I21 be used for primary diagnosis?

No, I21 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is I21 in?

I21 is in Chapter 9 of the ICD-10-CM Tabular List.

Is I21 valid for 2026?

Yes, I21 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousI20.9Angina pectoris, unspecifiedNext →I21.0ST elevation (STEMI) myocardial infarction of anterior wall
Code Details
I21
Acute myocardial infarction
Non-Billable / Non-Specific Code
9 — Diseases of the circulatory system (I00-I99)
I20-I25 — Ischemic heart diseases
2026 ICD-10-CM