T46
Non-Billable

Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system

Non-Billable / Non-Specific Code

What is Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system?

ICD-10-CM T46 is the diagnosis code for Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system. This code falls under the section "Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances" within Chapter 19 — Injury, poisoning and certain other consequences of external causes (S00-T88). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

⛔ Excludes1

Coding Guidelines for T46

⛔ Type 1 Excludes (Never code together)

The following conditions should never be coded at the same time as T46. They are mutually exclusive:

  • poisoning by, adverse effect of and underdosing of metaraminol (T44.4)

ICD-10-CM Code Hierarchy

Understanding where T46 sits in the ICD-10-CM classification helps ensure proper coding:

Sub-Codes 10 entries
T46.0Poisoning by, adverse effect of and underdosing of cardiac-stimulant glycosides and drugs of similar actionNon-BillableT46.0XPoisoning by, adverse effect of and underdosing of cardiac-stimulant glycosides and drugs of similar actionNon-BillableT46.0X1Poisoning by cardiac-stimulant glycosides and drugs of similar action, accidental (unintentional)BillableT46.0X2Poisoning by cardiac-stimulant glycosides and drugs of similar action, intentional self-harmBillableT46.0X3Poisoning by cardiac-stimulant glycosides and drugs of similar action, assaultBillableT46.0X4Poisoning by cardiac-stimulant glycosides and drugs of similar action, undeterminedBillableT46.0X5Adverse effect of cardiac-stimulant glycosides and drugs of similar actionBillableT46.0X6Underdosing of cardiac-stimulant glycosides and drugs of similar actionBillableT46.1Poisoning by, adverse effect of and underdosing of calcium-channel blockersNon-BillableT46.1XPoisoning by, adverse effect of and underdosing of calcium-channel blockersNon-BillableT46.1X1Poisoning by calcium-channel blockers, accidental (unintentional)BillableT46.1X2Poisoning by calcium-channel blockers, intentional self-harmBillableT46.1X3Poisoning by calcium-channel blockers, assaultBillableT46.1X4Poisoning by calcium-channel blockers, undeterminedBillableT46.1X5Adverse effect of calcium-channel blockersBillableT46.1X6Underdosing of calcium-channel blockersBillableT46.2Poisoning by, adverse effect of and underdosing of other antidysrhythmic drugs, not elsewhere classifiedNon-BillableT46.2XPoisoning by, adverse effect of and underdosing of other antidysrhythmic drugsNon-BillableT46.2X1Poisoning by other antidysrhythmic drugs, accidental (unintentional)BillableT46.2X2Poisoning by other antidysrhythmic drugs, intentional self-harmBillableT46.2X3Poisoning by other antidysrhythmic drugs, assaultBillableT46.2X4Poisoning by other antidysrhythmic drugs, undeterminedBillableT46.2X5Adverse effect of other antidysrhythmic drugsBillableT46.2X6Underdosing of other antidysrhythmic drugsBillableT46.3Poisoning by, adverse effect of and underdosing of coronary vasodilatorsNon-BillableT46.3XPoisoning by, adverse effect of and underdosing of coronary vasodilatorsNon-BillableT46.3X1Poisoning by coronary vasodilators, accidental (unintentional)BillableT46.3X2Poisoning by coronary vasodilators, intentional self-harmBillableT46.3X3Poisoning by coronary vasodilators, assaultBillableT46.3X4Poisoning by coronary vasodilators, undeterminedBillableT46.3X5Adverse effect of coronary vasodilatorsBillableT46.3X6Underdosing of coronary vasodilatorsBillableT46.4Poisoning by, adverse effect of and underdosing of angiotensin-converting-enzyme inhibitorsNon-BillableT46.4XPoisoning by, adverse effect of and underdosing of angiotensin-converting-enzyme inhibitorsNon-BillableT46.4X1Poisoning by angiotensin-converting-enzyme inhibitors, accidental (unintentional)BillableT46.4X2Poisoning by angiotensin-converting-enzyme inhibitors, intentional self-harmBillableT46.4X3Poisoning by angiotensin-converting-enzyme inhibitors, assaultBillableT46.4X4Poisoning by angiotensin-converting-enzyme inhibitors, undeterminedBillableT46.4X5Adverse effect of angiotensin-converting-enzyme inhibitorsBillableT46.4X6Underdosing of angiotensin-converting-enzyme inhibitorsBillableT46.5Poisoning by, adverse effect of and underdosing of other antihypertensive drugsNon-BillableT46.5XPoisoning by, adverse effect of and underdosing of other antihypertensive drugsNon-BillableT46.5X1Poisoning by other antihypertensive drugs, accidental (unintentional)BillableT46.5X2Poisoning by other antihypertensive drugs, intentional self-harmBillableT46.5X3Poisoning by other antihypertensive drugs, assaultBillableT46.5X4Poisoning by other antihypertensive drugs, undeterminedBillableT46.5X5Adverse effect of other antihypertensive drugsBillableT46.5X6Underdosing of other antihypertensive drugsBillableT46.6Poisoning by, adverse effect of and underdosing of antihyperlipidemic and antiarteriosclerotic drugsNon-BillableT46.6XPoisoning by, adverse effect of and underdosing of antihyperlipidemic and antiarteriosclerotic drugsNon-BillableT46.6X1Poisoning by antihyperlipidemic and antiarteriosclerotic drugs, accidental (unintentional)BillableT46.6X2Poisoning by antihyperlipidemic and antiarteriosclerotic drugs, intentional self-harmBillableT46.6X3Poisoning by antihyperlipidemic and antiarteriosclerotic drugs, assaultBillableT46.6X4Poisoning by antihyperlipidemic and antiarteriosclerotic drugs, undeterminedBillableT46.6X5Adverse effect of antihyperlipidemic and antiarteriosclerotic drugsBillableT46.6X6Underdosing of antihyperlipidemic and antiarteriosclerotic drugsBillableT46.7Poisoning by, adverse effect of and underdosing of peripheral vasodilatorsNon-BillableT46.7XPoisoning by, adverse effect of and underdosing of peripheral vasodilatorsNon-BillableT46.7X1Poisoning by peripheral vasodilators, accidental (unintentional)BillableT46.7X2Poisoning by peripheral vasodilators, intentional self-harmBillableT46.7X3Poisoning by peripheral vasodilators, assaultBillableT46.7X4Poisoning by peripheral vasodilators, undeterminedBillableT46.7X5Adverse effect of peripheral vasodilatorsBillableT46.7X6Underdosing of peripheral vasodilatorsBillableT46.8Poisoning by, adverse effect of and underdosing of antivaricose drugs, including sclerosing agentsNon-BillableT46.8XPoisoning by, adverse effect of and underdosing of antivaricose drugs, including sclerosing agentsNon-BillableT46.8X1Poisoning by antivaricose drugs, including sclerosing agents, accidental (unintentional)BillableT46.8X2Poisoning by antivaricose drugs, including sclerosing agents, intentional self-harmBillableT46.8X3Poisoning by antivaricose drugs, including sclerosing agents, assaultBillableT46.8X4Poisoning by antivaricose drugs, including sclerosing agents, undeterminedBillableT46.8X5Adverse effect of antivaricose drugs, including sclerosing agentsBillableT46.8X6Underdosing of antivaricose drugs, including sclerosing agentsBillableT46.9Poisoning by, adverse effect of and underdosing of other and unspecified agents primarily affecting the cardiovascular systemNon-BillableT46.90Poisoning by, adverse effect of and underdosing of unspecified agents primarily affecting the cardiovascular systemNon-BillableT46.901Poisoning by unspecified agents primarily affecting the cardiovascular system, accidental (unintentional)BillableT46.902Poisoning by unspecified agents primarily affecting the cardiovascular system, intentional self-harmBillableT46.903Poisoning by unspecified agents primarily affecting the cardiovascular system, assaultBillableT46.904Poisoning by unspecified agents primarily affecting the cardiovascular system, undeterminedBillableT46.905Adverse effect of unspecified agents primarily affecting the cardiovascular systemBillableT46.906Underdosing of unspecified agents primarily affecting the cardiovascular systemBillableT46.99Poisoning by, adverse effect of and underdosing of other agents primarily affecting the cardiovascular systemNon-BillableT46.991Poisoning by other agents primarily affecting the cardiovascular system, accidental (unintentional)BillableT46.992Poisoning by other agents primarily affecting the cardiovascular system, intentional self-harmBillableT46.993Poisoning by other agents primarily affecting the cardiovascular system, assaultBillableT46.994Poisoning by other agents primarily affecting the cardiovascular system, undeterminedBillableT46.995Adverse effect of other agents primarily affecting the cardiovascular systemBillableT46.996Underdosing of other agents primarily affecting the cardiovascular systemBillable
Related Codes

Frequently Asked Questions

Is T46 a billable ICD-10-CM code?

No, T46 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does T46 mean?

T46 is the ICD-10-CM diagnosis code for "Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What section is T46 in?

T46 is located in Section T36-T50 — "Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances" within Chapter 19 of the ICD-10-CM Tabular List.

What are the sub-codes of T46?

T46 has 10 sub-code(s) that provide more specific detail: T46.0, T46.1, T46.2, T46.3, T46.4 and more.

When should I use T46?

Use T46 when the patients documented diagnosis matches "Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system?

The ICD-10-CM code for Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system is T46.

Can T46 be used for primary diagnosis?

No, T46 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is T46 in?

T46 is in Chapter 19 of the ICD-10-CM Tabular List.

What conditions are excluded from T46?

Type 1 Excludes for T46 include: poisoning by, adverse effect of and underdosing of metaraminol (T44.4).

Is T46 valid for 2026?

Yes, T46 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousT45.AX6Underdosing of immune checkpoint inhibitors and immunostimulant drugsNext →T46.0Poisoning by, adverse effect of and underdosing of cardiac-stimulant glycosides and drugs of similar action
Code Details
T46
Poisoning by, adverse effect of and underdosing of agents primarily affecting the cardiovascular system
Non-Billable / Non-Specific Code
19 — Injury, poisoning and certain other consequences of external causes (S00-T88)
T36-T50 — Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
2026 ICD-10-CM