T80.5
Non-Billable

Anaphylactic reaction due to serum

Non-Billable / Non-Specific Code

What is Anaphylactic reaction due to serum?

ICD-10-CM T80.5 is the diagnosis code for Anaphylactic reaction due to serum. This code falls under the section "Complications of surgical and medical care, not elsewhere classified" within Chapter 19 — Injury, poisoning and certain other consequences of external causes (S00-T88). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

💡 Inclusions
⛔ Excludes1

Coding Guidelines for T80.5

✅ This Code Includes

  • Allergic shock due to serum
  • Anaphylactic shock due to serum
  • Anaphylactoid reaction due to serum
  • Anaphylaxis due to serum

⛔ Type 1 Excludes (Never code together)

The following conditions should never be coded at the same time as T80.5. They are mutually exclusive:

  • ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
  • allergic reaction or shock NOS (T78.2)
  • anaphylactic reaction or shock NOS (T78.2)
  • anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
  • other serum reaction (T80.6-)

ICD-10-CM Code Hierarchy

Understanding where T80.5 sits in the ICD-10-CM classification helps ensure proper coding:

Sub-Codes 3 entries
T80.51Anaphylactic reaction due to administration of blood and blood productsBillableT80.52Anaphylactic reaction due to vaccinationBillableT80.59Anaphylactic reaction due to other serumBillable
Related Codes

Frequently Asked Questions

Is T80.5 a billable ICD-10-CM code?

No, T80.5 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does T80.5 mean?

T80.5 is the ICD-10-CM diagnosis code for "Anaphylactic reaction due to serum". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What is the parent code of T80.5?

The parent code of T80.5 is T80 ("Complications following infusion, transfusion and therapeutic injection"). T80.5 provides a more specific classification within this category.

What section is T80.5 in?

T80.5 is located in Section T80-T88 — "Complications of surgical and medical care, not elsewhere classified" within Chapter 19 of the ICD-10-CM Tabular List.

What are the sub-codes of T80.5?

T80.5 has 3 sub-code(s) that provide more specific detail: T80.51, T80.52, T80.59.

When should I use T80.5?

Use T80.5 when the patients documented diagnosis matches "Anaphylactic reaction due to serum" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Anaphylactic reaction due to serum?

The ICD-10-CM code for Anaphylactic reaction due to serum is T80.5.

Can T80.5 be used for primary diagnosis?

No, T80.5 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is T80.5 in?

T80.5 is in Chapter 19 of the ICD-10-CM Tabular List.

What conditions are excluded from T80.5?

Type 1 Excludes for T80.5 include: ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-); allergic reaction or shock NOS (T78.2); anaphylactic reaction or shock NOS (T78.2) and more.

Is T80.5 valid for 2026?

Yes, T80.5 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousT80.49Other Rh incompatibility reaction due to transfusion of blood or blood productsNext →T80.51Anaphylactic reaction due to administration of blood and blood products
Code Details
T80.5
Anaphylactic reaction due to serum
Non-Billable / Non-Specific Code
19 — Injury, poisoning and certain other consequences of external causes (S00-T88)
T80-T88 — Complications of surgical and medical care, not elsewhere classified
2026 ICD-10-CM