E78
Non-Billable

Disorders of lipoprotein metabolism and other lipidemias

Non-Billable / Non-Specific Code

What is Disorders of lipoprotein metabolism and other lipidemias?

ICD-10-CM E78 is the diagnosis code for Disorders of lipoprotein metabolism and other lipidemias. This code falls under the section "Metabolic disorders" within Chapter 4 — Endocrine, nutritional and metabolic diseases (E00-E89). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

⛔ Excludes1

Coding Guidelines for E78

⛔ Type 1 Excludes (Never code together)

The following conditions should never be coded at the same time as E78. They are mutually exclusive:

  • sphingolipidosis (E75.0-E75.3)

ICD-10-CM Code Hierarchy

Understanding where E78 sits in the ICD-10-CM classification helps ensure proper coding:

Current CodeE78 — Disorders of lipoprotein metabolism and other lipidemias
Sub-Codes 10 entries
E78.0Pure hypercholesterolemiaNon-BillableE78.00Pure hypercholesterolemia, unspecifiedBillableE78.01Familial hypercholesterolemiaNon-BillableE78.010Homozygous familial hypercholesterolemia [HoFH]BillableE78.011Heterozygous familial hypercholesterolemia [HeFH]BillableE78.019Familial hypercholesterolemia, unspecifiedBillableE78.1Pure hyperglyceridemiaBillableE78.2Mixed hyperlipidemiaBillableE78.3HyperchylomicronemiaBillableE78.4Other hyperlipidemiaNon-BillableE78.41Elevated Lipoprotein(a)BillableE78.49Other hyperlipidemiaBillableE78.5Hyperlipidemia, unspecifiedBillableE78.6Lipoprotein deficiencyBillableE78.7Disorders of bile acid and cholesterol metabolismNon-BillableE78.70Disorder of bile acid and cholesterol metabolism, unspecifiedBillableE78.71Barth syndromeBillableE78.72Smith-Lemli-Opitz syndromeBillableE78.79Other disorders of bile acid and cholesterol metabolismBillableE78.8Other disorders of lipoprotein metabolismNon-BillableE78.81Lipoid dermatoarthritisBillableE78.89Other lipoprotein metabolism disordersBillableE78.9Disorder of lipoprotein metabolism, unspecifiedBillable
Related Codes

Frequently Asked Questions

Is E78 a billable ICD-10-CM code?

No, E78 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does E78 mean?

E78 is the ICD-10-CM diagnosis code for "Disorders of lipoprotein metabolism and other lipidemias". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What section is E78 in?

E78 is located in Section E70-E88 — "Metabolic disorders" within Chapter 4 of the ICD-10-CM Tabular List.

What are the sub-codes of E78?

E78 has 10 sub-code(s) that provide more specific detail: E78.0, E78.1, E78.2, E78.3, E78.4 and more.

When should I use E78?

Use E78 when the patients documented diagnosis matches "Disorders of lipoprotein metabolism and other lipidemias" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Disorders of lipoprotein metabolism and other lipidemias?

The ICD-10-CM code for Disorders of lipoprotein metabolism and other lipidemias is E78.

Can E78 be used for primary diagnosis?

No, E78 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is E78 in?

E78 is in Chapter 4 of the ICD-10-CM Tabular List.

What conditions are excluded from E78?

Type 1 Excludes for E78 include: sphingolipidosis (E75.0-E75.3).

Is E78 valid for 2026?

Yes, E78 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousE77.9Disorder of glycoprotein metabolism, unspecifiedNext →E78.0Pure hypercholesterolemia
Code Details
E78
Disorders of lipoprotein metabolism and other lipidemias
Non-Billable / Non-Specific Code
4 — Endocrine, nutritional and metabolic diseases (E00-E89)
E70-E88 — Metabolic disorders
2026 ICD-10-CM