Billable / Specific Code
ICD-10-CM R65.10 is the diagnosis code for Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction. This code falls under the section "General symptoms and signs" within Chapter 18 — Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99). It is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.
Understanding where R65.10 sits in the ICD-10-CM classification helps ensure proper coding:
Yes, R65.10 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.
R65.10 is the ICD-10-CM diagnosis code for "Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.
The parent code of R65.10 is R65.1 ("Systemic inflammatory response syndrome (SIRS) of non-infectious origin"). R65.10 provides a more specific classification within this category.
R65.10 is located in Section R50-R69 — "General symptoms and signs" within Chapter 18 of the ICD-10-CM Tabular List.
Use R65.10 when the patients documented diagnosis matches "Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.
The ICD-10-CM code for Systemic inflammatory response syndrome (SIRS) of non-infectious origin without acute organ dysfunction is R65.10.
Yes, R65.10 can be used as a primary diagnosis code since it is billable and specific.
R65.10 is in Chapter 18 of the ICD-10-CM Tabular List.
Yes, R65.10 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.