D80
Non-Billable

Immunodeficiency with predominantly antibody defects

Non-Billable / Non-Specific Code

What is Immunodeficiency with predominantly antibody defects?

ICD-10-CM D80 is the diagnosis code for Immunodeficiency with predominantly antibody defects. This code falls under the section "Certain disorders involving the immune mechanism" within Chapter 3 — Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

Coding Guidelines for D80

Always refer to the official ICD-10-CM Tabular List for complete coding guidelines. Ensure documentation supports the specificity of the code selected. When in doubt, consult a certified medical coder or the latest CMS guidelines.

ICD-10-CM Code Hierarchy

Understanding where D80 sits in the ICD-10-CM classification helps ensure proper coding:

Sub-Codes 10 entries
D80.0Hereditary hypogammaglobulinemiaBillableD80.1Nonfamilial hypogammaglobulinemiaBillableD80.2Selective deficiency of immunoglobulin A [IgA]BillableD80.3Selective deficiency of immunoglobulin G [IgG] subclassesBillableD80.4Selective deficiency of immunoglobulin M [IgM]BillableD80.5Immunodeficiency with increased immunoglobulin M [IgM]BillableD80.6Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemiaBillableD80.7Transient hypogammaglobulinemia of infancyBillableD80.8Other immunodeficiencies with predominantly antibody defectsBillableD80.9Immunodeficiency with predominantly antibody defects, unspecifiedBillable
Related Codes

Frequently Asked Questions

Is D80 a billable ICD-10-CM code?

No, D80 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does D80 mean?

D80 is the ICD-10-CM diagnosis code for "Immunodeficiency with predominantly antibody defects". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What section is D80 in?

D80 is located in Section D80-D89 — "Certain disorders involving the immune mechanism" within Chapter 3 of the ICD-10-CM Tabular List.

What are the sub-codes of D80?

D80 has 10 sub-code(s) that provide more specific detail: D80.0, D80.1, D80.2, D80.3, D80.4 and more.

When should I use D80?

Use D80 when the patients documented diagnosis matches "Immunodeficiency with predominantly antibody defects" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Immunodeficiency with predominantly antibody defects?

The ICD-10-CM code for Immunodeficiency with predominantly antibody defects is D80.

Can D80 be used for primary diagnosis?

No, D80 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is D80 in?

D80 is in Chapter 3 of the ICD-10-CM Tabular List.

Is D80 valid for 2026?

Yes, D80 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousD78.89Other postprocedural complications of the spleenNext →D80.0Hereditary hypogammaglobulinemia
Code Details
D80
Immunodeficiency with predominantly antibody defects
Non-Billable / Non-Specific Code
3 — Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
D80-D89 — Certain disorders involving the immune mechanism
2026 ICD-10-CM