E74.4
Billable

Disorders of pyruvate metabolism and gluconeogenesis

Billable / Specific Code

What is Disorders of pyruvate metabolism and gluconeogenesis?

ICD-10-CM E74.4 is the diagnosis code for Disorders of pyruvate metabolism and gluconeogenesis. This code falls under the section "Metabolic disorders" within Chapter 4 — Endocrine, nutritional and metabolic diseases (E00-E89). It is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

💡 Inclusions
⛔ Excludes1

Coding Guidelines for E74.4

✅ This Code Includes

  • Deficiency of phosphoenolpyruvate carboxykinase
  • Deficiency of pyruvate carboxylase
  • Deficiency of pyruvate dehydrogenase

⛔ Type 1 Excludes (Never code together)

The following conditions should never be coded at the same time as E74.4. They are mutually exclusive:

  • disorders of pyruvate metabolism and gluconeogenesis with anemia (D55.-)
  • Leigh's syndrome (G31.82)

ICD-10-CM Code Hierarchy

Understanding where E74.4 sits in the ICD-10-CM classification helps ensure proper coding:

Current CodeE74.4 — Disorders of pyruvate metabolism and gluconeogenesis
Related Codes

Frequently Asked Questions

Is E74.4 a billable ICD-10-CM code?

Yes, E74.4 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes.

What does E74.4 mean?

E74.4 is the ICD-10-CM diagnosis code for "Disorders of pyruvate metabolism and gluconeogenesis". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What is the parent code of E74.4?

The parent code of E74.4 is E74 ("Other disorders of carbohydrate metabolism"). E74.4 provides a more specific classification within this category.

What section is E74.4 in?

E74.4 is located in Section E70-E88 — "Metabolic disorders" within Chapter 4 of the ICD-10-CM Tabular List.

When should I use E74.4?

Use E74.4 when the patients documented diagnosis matches "Disorders of pyruvate metabolism and gluconeogenesis" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Disorders of pyruvate metabolism and gluconeogenesis?

The ICD-10-CM code for Disorders of pyruvate metabolism and gluconeogenesis is E74.4.

Can E74.4 be used for primary diagnosis?

Yes, E74.4 can be used as a primary diagnosis code since it is billable and specific.

What chapter is E74.4 in?

E74.4 is in Chapter 4 of the ICD-10-CM Tabular List.

What conditions are excluded from E74.4?

Type 1 Excludes for E74.4 include: disorders of pyruvate metabolism and gluconeogenesis with anemia (D55.-); Leigh's syndrome (G31.82).

Is E74.4 valid for 2026?

Yes, E74.4 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousE74.39Other disorders of intestinal carbohydrate absorptionNext →E74.8Other specified disorders of carbohydrate metabolism
Code Details
E74.4
Disorders of pyruvate metabolism and gluconeogenesis
Billable / Specific Code
4 — Endocrine, nutritional and metabolic diseases (E00-E89)
E70-E88 — Metabolic disorders
2026 ICD-10-CM