M35
Non-Billable

Other systemic involvement of connective tissue

Non-Billable / Non-Specific Code

What is Other systemic involvement of connective tissue?

ICD-10-CM M35 is the diagnosis code for Other systemic involvement of connective tissue. This code falls under the section "Systemic connective tissue disorders" within Chapter 13 — Diseases of the musculoskeletal system and connective tissue (M00-M99). It is a non-billable/non-specific ICD-10-CM code that should not be used for reimbursement. A more specific sub-code is required for billing. Medical coders and healthcare providers use this code to document and classify diagnoses in electronic health records, insurance claims, and clinical databases.

⛔ Excludes1

Coding Guidelines for M35

⛔ Type 1 Excludes (Never code together)

The following conditions should never be coded at the same time as M35. They are mutually exclusive:

  • reactive perforating collagenosis (L87.1)

ICD-10-CM Code Hierarchy

Understanding where M35 sits in the ICD-10-CM classification helps ensure proper coding:

Sub-Codes 10 entries
M35.0Sjögren syndromeNon-BillableM35.00Sjögren syndrome, unspecifiedBillableM35.01Sjögren syndrome with keratoconjunctivitisBillableM35.02Sjögren syndrome with lung involvementBillableM35.03Sjögren syndrome with myopathyBillableM35.04Sjögren syndrome with tubulo-interstitial nephropathyBillableM35.05Sjögren syndrome with inflammatory arthritisBillableM35.06Sjögren syndrome with peripheral nervous system involvementBillableM35.07Sjögren syndrome with central nervous system involvementBillableM35.08Sjögren syndrome with gastrointestinal involvementBillableM35.09Sjögren syndrome with other organ involvementBillableM35.0ASjögren syndrome with glomerular diseaseBillableM35.0BSjögren syndrome with vasculitisBillableM35.0CSjögren syndrome with dental involvementBillableM35.1Other overlap syndromesBillableM35.2Behçet's diseaseBillableM35.3Polymyalgia rheumaticaBillableM35.4Diffuse (eosinophilic) fasciitisBillableM35.5Multifocal fibrosclerosisBillableM35.6Relapsing panniculitis [Weber-Christian]BillableM35.7Hypermobility syndromeBillableM35.8Other specified systemic involvement of connective tissueNon-BillableM35.81Multisystem inflammatory syndromeBillableM35.89Other specified systemic involvement of connective tissueBillableM35.9Systemic involvement of connective tissue, unspecifiedBillable
Related Codes

Frequently Asked Questions

Is M35 a billable ICD-10-CM code?

No, M35 is a non-billable/non-specific code. You should use a more specific sub-code for billing and reimbursement.

What does M35 mean?

M35 is the ICD-10-CM diagnosis code for "Other systemic involvement of connective tissue". It is used by healthcare providers to classify and document this condition in medical records and insurance claims.

What section is M35 in?

M35 is located in Section M30-M36 — "Systemic connective tissue disorders" within Chapter 13 of the ICD-10-CM Tabular List.

What are the sub-codes of M35?

M35 has 10 sub-code(s) that provide more specific detail: M35.0, M35.1, M35.2, M35.3, M35.4 and more.

When should I use M35?

Use M35 when the patients documented diagnosis matches "Other systemic involvement of connective tissue" and the clinical documentation supports this level of specificity. Always verify with the latest ICD-10-CM guidelines and payer requirements.

People Also Ask

What is the ICD-10 code for Other systemic involvement of connective tissue?

The ICD-10-CM code for Other systemic involvement of connective tissue is M35.

Can M35 be used for primary diagnosis?

No, M35 is non-billable. Use a more specific sub-code for primary diagnosis billing.

What chapter is M35 in?

M35 is in Chapter 13 of the ICD-10-CM Tabular List.

What conditions are excluded from M35?

Type 1 Excludes for M35 include: reactive perforating collagenosis (L87.1).

Is M35 valid for 2026?

Yes, M35 is a valid ICD-10-CM code for the 2026 fiscal year, subject to official CMS updates.

See Also

← PreviousM34.9Systemic sclerosis, unspecifiedNext →M35.0Sjögren syndrome
Code Details
M35
Other systemic involvement of connective tissue
Non-Billable / Non-Specific Code
13 — Diseases of the musculoskeletal system and connective tissue (M00-M99)
M30-M36 — Systemic connective tissue disorders
2026 ICD-10-CM